11-β-羥基類固醇脫氫酶1(HSD11b1)重組蛋白
Recombinant 11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11b1)
11DH; 11-beta-HSD1; HDL; HSD11; HSD11B; HSD11L; SDR26C1; Corticosteroid 11-beta-dehydrogenase isozyme 1; Short Chain Dehydrogenase/Reductase Family 26C,Member 1
- 編號RPC268Ra01
- 物種Rattus norvegicus (Rat，大鼠)相同的名稱，不同的物種。
- 來源原核表達
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位細胞膜
- 預(yù)測分子量35.6kDa
- 實際分子量33kDa(差異分析請參閱說明書)
- 片段與標簽Met1~Asn288 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 95%
- 等電點8.6
- 應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載英文說明書 中文說明書
- 規(guī)格10μg50μg200μg1mg5mg
- 價格¥ 1104¥ 2760¥ 5520¥ 16560¥ 41400
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
Figure. SDS-PAGE
通過ISO 9001、ISO 13485質(zhì)量體系認證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復(fù)凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPC268Ra01 | 11-β-羥基類固醇脫氫酶1(HSD11b1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAC268Ra01 | 11-β-羥基類固醇脫氫酶1(HSD11b1)多克隆抗體 | WB; IHC; ICC; IP. |
| MAC268Ra21 | 11-β-羥基類固醇脫氫酶1(HSD11b1)單克隆抗體 | WB; IHC; ICC; IP. |
| SEC268Ra | 11-β-羥基類固醇脫氫酶1(HSD11b1)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMC268Ra | 11-β-羥基類固醇脫氫酶1(HSD11b1)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Journal of Endocrinology | Uninephrectomy reduces 11β-hydroxysteroid dehydrogenase type 1 and type 2 concomitantly with an increase in blood pressure in rats [PubMed: 22739210] |
| Evid Based Complement Alternat Med | Anti-Inflammatory Property of[PubMed: 26300946] |
| Molecules | Piper?sarmentosum?Effects?on 11β-Hydroxysteroid?Dehydrogenase?Type?1?Enzyme?in?Serumand?Bone?in?Rat?Model?of?Glucocorticoid-Induced?Osteoporosis.[pubmed:27854305] |
| Bioorganic Chemistry | A novel derivatives of thiazol-4 (5H)-one and their activity in the inhibition of 11β-hydroxysteroid dehydrogenase type 1[Pubmed:29738970] |
| Malaysian Journal of?Medical?Sciences | An Evidence-Based Review: The Effects of Malaysian Traditional Herbs on Osteoporotic Rat Models[] |
| 2.583 | Application of ELISA Technique and Human Microsomes in the Search for 11β-Hydroxysteroid Dehydrogenase Inhibitors[Doi: BioMed Research International] |
| Chemistry & Biodiversity | Synthesis of the N‐methyl derivatives of 2‐aminothiazol‐4 (5H)‐one and their interactions with 11βHSD1‐molecular modeling and in vitro studies[Pubmed: 31012543] |
| Oxidative Medicine and Cellular Longevity | Hepatoprotective Effects of Morinda citrifolia Leaf Extract on Ovariectomized Rats Fed with Thermoxidized Palm Oil Diet: Evidence at Histological and Ultrastructural?…[Pubmed: 31827717] |