肝素結(jié)合性表皮生長(zhǎng)因子(HBEGF)活性蛋白
Active Heparin Binding Epidermal Growth Factor Like Growth Factor (HBEGF)
HB-EGF; DTR; DTS; DTSF; HEGFL; Diphtheria Toxin Receptor; Proheparin-binding EGF-like growth factor; Diphtheria toxin receptor
- 編號(hào)APB479Hu61
- 物種Homo sapiens (Human，人)相同的名稱，不同的物種。
- 緩沖液成份磷酸鹽緩沖液（pH7.4，含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.）
- 性狀凍干粉
- 純度> 97%
- 等電點(diǎn)9.7
- 應(yīng)用Cell?culture;?Activity?Assays.
- 下載英文說(shuō)明書(shū) 中文說(shuō)明書(shū)
- 規(guī)格10μg50μg200μg1mg5mg
- 價(jià)格¥ 1248¥ 3120¥ 6240¥ 18720¥ 46800
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
SDS-PAGE圖
通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
活性實(shí)驗(yàn)
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過(guò)一個(gè)月，-80°C不超過(guò)12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
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參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Neuropathology | Astrocyte ERK phosphorylation precedes K+-induced swelling but follows hypotonicity-induced swelling.[PubMed: 21118399] |
| Toxicological Sciences | Cypermethrin Induces Astrocyte Apoptosis by the Disruption of the Autocrine/Paracrine Mode of Epidermal Growth Factor Receptor Signaling[Pubmed: source] |
| PAIN RESEARCH | 軽度炎癥性膀胱痛マウスモデルの構(gòu)築とNGFの関與[Jstage:Source] |
| European Journal of Pain | A?novel?method?for?assessing?bladder-related?pain?reveals?the?involvement?of?nerve?growth?factor?in?painassociated?with?cyclophosphamide-induced?chronic?cystitis?in?mice.[Pubmed:25820250] |
| Kinki daigaku | 2 型糖尿病モデルラットにおける糖尿病性腎癥の進(jìn)行とHB-EGF の関連性[17844] |
| laboratory investigation | Heparin-binding epidermal growth factor contributes to COPD disease severity by modulating airway fibrosis and pulmonary epithelial–mesenchymal transition[Pubmed:29581578] |
| International Journal of Biological Sciences | CD9 regulates keratinocyte migration by negatively modulating the sheddase activity of ADAM17[] |
| Redox?Biology | Tumoral NOX4 recruits M2 tumor-associated macrophages via ROS/PI3K signaling-dependent various cytokine production to promote NSCLC growth[Pubmed: 30769285] |
| JOURNAL OF CELLULAR AND MOLECULAR MEDICINE | Polarization of ADAM17‐driven EGFR signalling in electric field‐guided collective migration of epidermal sheets[Pubmed: 33164313] |
| 象牙芽細(xì)胞の枯渇は象牙芽細(xì)胞分化と象牙質(zhì)形成を誘導(dǎo)する[] |