淀粉樣前體蛋白(APP)多克隆抗體
Polyclonal Antibody to Amyloid Precursor Protein (APP)
AAA; ABeta; ABPP; AD1; APPI; CVAP; PN2; CTFgamma; Peptidase Nexin-II Alzheimer Disease; Peptidase Nexin-II; Amyloid Beta(A4)Precursor Protein
- 編號PAB020Mu01
- 物種Mus musculus (Mouse，小鼠)相同的名稱，不同的物種。
- 來源多抗制備
- 宿主兔
- 效價-
- Ig類型IgG
- 純化方式抗原特異性親和純化
- 標記物無標記物
- 免疫原RPB020Mu01-淀粉樣前體蛋白(APP)重組蛋白
- 緩沖液成份磷酸鹽緩沖液（pH7.4,含有0.02% NaN3和50%甘油）
- 性狀液體
- 濃度500μg/mL
- 且適物種Homo sapiens (Human，人)
- 應(yīng)用WB; IHC
如果抗體需用于流式細胞術(shù)，請參見流式抗體。 - 下載英文說明書 中文說明書
- 規(guī)格20μl100μl200μl1ml10ml
- 價格¥ 616¥ 1436¥ 2052¥ 5130¥ 20520
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
DAB staining on IHC-P; Sample: Mouse Cerebrum Tissue Primary Ab: 10μg/ml Rabbit Anti-Mouse APP Antibody Control: Used PBS instead of primary antibody Second Ab: 2μg/ml HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
DAB staining on IHC-P;
Samples: Mouse Testis Tissue;
Primary Ab: 20μg/ml Rabbit Anti-Mouse APP Antibody
Second Ab: 2μg/mL?HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb19)
Western Blot; Sample: SK-N-SH cell lysate Primary Ab: 0.5μg/ml Rabbit Anti-Mouse APP Antibody Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19)
Western Blot; Sample: Mouse Cerebrum lysate
Primary Ab: 0.3μg/ml Rabbit Anti-Mouse APP Antibody
Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb19)
Western Blot; Sample: 293T cell lysate
Primary Ab: 0.5μg/ml Rabbit Anti-Mouse APP Antibody
Second Ab: 0.2μg/ml HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
(Catalog: SAA544Rb19)
通過ISO 9001、ISO 13485質(zhì)量體系認證
特異性
該抗體是針對APP的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別APP。
用法
Western blotting: 0.5-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當?shù)臈l件下存儲，損失率低于5%。
贈品
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Mus musculus (Mouse，小鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPB020Mu01 | 淀粉樣前體蛋白(APP)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB020Mu02 | 淀粉樣前體蛋白(APP)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB020Mu02 | 淀粉樣前體蛋白(APP)多克隆抗體 | WB; IHC; ICC; IP. |
| PAB020Mu01 | 淀粉樣前體蛋白(APP)多克隆抗體 | WB; IHC |
| LAB020Mu81 | 淀粉樣前體蛋白(APP)多克隆抗體(異硫氰酸熒光素標記) | WB; IHC; ICC; IF. |
| LAB020Mu71 | 淀粉樣前體蛋白(APP)多克隆抗體(生物素標記) | WB; IHC; ICC. |
| MEB020Mu | 淀粉樣前體蛋白(APP)檢測試劑盒(酶聯(lián)免疫吸附試驗法,小樣本) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SEB020Mu | 淀粉樣前體蛋白(APP)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB020Mu | 淀粉樣前體蛋白(APP)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| Neurochemistry International | Bilobalide regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase-dependent pathway[ScienceDirect: S0197018611001641] |
| Neuroscience | Substitution of membrane cholesterol with β-sitosterol promotes nonamyloidogenic cleavage of endogenous amyloid precursor protein[Pubmed: 23707801] |
| OncoImmunology | PROOF COVER SHEET[] |
| 臺灣農(nóng)業(yè)研究 | (臺灣農(nóng)業(yè)研究67 (4): 355-364) 香菇柄水萃物改善糖尿病降低阿茲海默氏癥罹病風(fēng)險初探[] |
| Neurotoxicology | Involvement of hippocampal agmatine in β1-42 amyloid induced memory impairment, neuroinflammation and BDNF signaling disruption in mice[Pubmed: 32522471] |
| Metab Brain Dis | Probiotics ameliorates LPS induced neuroinflammation injury on Aβ 1–42, APP, γ-β secretase and BDNF levels in maternal gut microbiota and fetal?…[Pubmed:35312928] |
| Exp Gerontol | The positive impact of 12 weeks of dance and balance training on the circulating amyloid precursor protein and serotonin concentration as well as physical and?…[Pubmed:35217193] |