B-細(xì)胞淋巴瘤因子2(Bcl2)重組蛋白
Recombinant B-Cell Leukemia/Lymphoma 2 (Bcl2)
B-Cell CLL/Lymphoma 2
- 編號(hào)RPA778Mu01
- 物種Mus musculus (Mouse，小鼠)相同的名稱，不同的物種。
- 來(lái)源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
- 亞細(xì)胞定位外泌體
- 預(yù)測(cè)分子量27.2kDa
- 實(shí)際分子量28kDa(差異分析請(qǐng)參閱說(shuō)明書(shū))
- 片段與標(biāo)簽Ala2~Asp208 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 97%
- 等電點(diǎn)6.7
- 應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見(jiàn)活性蛋白。 - 下載英文說(shuō)明書(shū) 中文說(shuō)明書(shū)
- 規(guī)格10μg50μg200μg1mg5mg
- 價(jià)格¥ 840¥ 2100¥ 4200¥ 12600¥ 31500
- 欲了解實(shí)際交易價(jià)格和更多情況，請(qǐng)與當(dāng)?shù)亟?jīng)銷商聯(lián)系!
產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
SDS-PAGE圖
通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過(guò)一個(gè)月，-80°C不超過(guò)12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Mus musculus (Mouse，小鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPA778Mu01 | B-細(xì)胞淋巴瘤因子2(Bcl2)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPA778Mu02 | B-細(xì)胞淋巴瘤因子2(Bcl2)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA778Mu01 | B-細(xì)胞淋巴瘤因子2(Bcl2)多克隆抗體 | WB; IHC; ICC/IF |
| PAA778Mu02 | B-細(xì)胞淋巴瘤因子2(Bcl2)多克隆抗體 | WB; IHC; ICC; IP. |
| LAA778Mu81 | B-細(xì)胞淋巴瘤因子2(Bcl2)多克隆抗體(異硫氰酸熒光素標(biāo)記) | WB; IHC; ICC; IF. |
| LAA778Mu71 | B-細(xì)胞淋巴瘤因子2(Bcl2)多克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
| SEA778Mu | B-細(xì)胞淋巴瘤因子2(Bcl2)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| MEA778Mu | B-細(xì)胞淋巴瘤因子2(Bcl2)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法,小樣本) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA778Mu | B-細(xì)胞淋巴瘤因子2(Bcl2)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| Anticancer Research | Analysis of p53 and miRNA expression after irradiation of glioblastoma cell lines[PubMed: 23155233] |
| International Journal of Health Sciences | Neurotoxic effect of lead on rats: Relationship to Apoptosis[NCBI: PMC3883608] |
| Interactive cardiovascular and thoracic surgery | Effects of hepatocyte growth factor in myocarditis rats induced by immunization with porcine cardiac myosin[Pubmed: 24327573] |
| J Physiol Biochem. | Vitamin D ameliorates hepatic ischemic/reperfusion injury in rats[Pubmed:24752458] |
| Chem Biol Interact.? | Gastroprotective effect of nymphayol isolated from Nymphaea stellata (Willd.) flowers: Contribution of antioxidant, anti-inflammatory and anti-apoptotic activities[Pubmed:25289771] |
| Pediatric Cardiology | Serum Bcl-2 Values in Children with Pulmonary Hypertension[Pubmed:25381623] |
| Histochem Cell Biol. | Inhibition of small HA fragment activity and stimulation of A2A adenosine receptor pathway limit apoptosis and reduce cartilage damage in experimental arthritis[Pubmed:25511416] |
| PLOS ONE | Mangiferin Mitigates Gastric Ulcer in Ischemia/ Reperfused Rats: Involvement of PPAR-γ, NF-κB and Nrf2/HO-1 Signaling Pathways[PubMed: 26196679] |
| Neurochem Res | Protective Effect of Oral Hesperetin Against Unilateral Striatal 6-Hydroxydopamine Damage in the Rat[PubMed: 26700436] |
| European Journal of Medicinal Plants | Hepatoprotective Effects of Rubus idaeus L. Leaves against CCl4-Induced Liver Injury via Antioxidant, Anti-inflammatory and Antiapoptotic Mechanisms[openview:626440] |
| IJBPAS | THE PROPHYLACTIC EFFICIENCY OF LYCOPENE AGAINST GAMMA IRRADAITION-INDIUCED CARDIAC OXIDATIVE DAMAGE, PATHOLOGY AND APOPTOSIS IN RATS[publication:298838934] |
| Mol Neurobiol. | Neuroprotective Effect of Nanodiamond in Alzheimer's Disease Rat Model: a Pivotal Role for Modulating NF-κB and STAT3 Signaling[Pubmed:26897372] |
| Iranian Journal of Basic Medical Sciences | The ameliorative potential of ethanolic extract of propolis on hematotoxicity and structural neuronal damage in hyperthermia-exposed rats[pubmed:27746870] |
| Scientific Reports | In Vivo Characterization of ARN14140, a Memantine/Galantamine-Based Multi-Target Compound for Alzheimer's Disease[pubmed:27609215] |
| IOS Press Content Library | An Intranasal Formulation of Erythropoietin (Neuro-EPO) Prevents Memory Deficits and Amyloid Toxicity in the APPSwe Transgenic Mouse Model of Alzheimer's …[articles:journal-of-alzheimers-disease] |
| Journal?of?Ethnopharmacology | Amelioration?of?cardiac?dysfunction?and?ventricular?remodeling?after?myocardial?infarction?bydanhong?injection?are?critically?contributed by anti-TGF-β-mediated fibrosis and angiogenesis mechanisms.[pubmed:27729285] |
| European Journal of Pharmacology | Mangiferin protects against? intestinal ischemia/reperfusion-induced? liver injury:?? Involvement of PPAR-? γ, GSK-3β and Wnt/β-catenin pathway????????????????????????????????????????????????[pubmed:28506911] |
| Journal of Applied Pharmaceutical Science | Comparative Effects of Stevia rebaudiana and Aspartame on hepato-renal function of diabetic rats: Biochemical and Histological Approaches[59b5141c458515a5b49377cf] |
| Cellular Physiology and Biochemistry | A Novel Role of SIRT1/ FGF-21 in Taurine Protection Against Cafeteria Diet-Induced Steatohepatitis in Rats[pubmed:28942443] |
| Biomedicine & Pharmacotherapy | Mechanistic insights into the effects of quercetin and/or GLP-1 analogue liraglutide on high-fat diet/streptozotocin-induced type 2 diabetes in rats[pubmed:28554128] |
| Thromb Haemost | Distinctive expression signatures of serum microRNAs in ischaemic stroke and transient ischaemic attack patients[pubmed:28251236] |
| International Journal of Biological Macromolecules | A polysaccharide (PNPA) from Pleurotus nebrodensis ameliorates hepatic ischemic/reperfusion (I/R) injury in rats[pubmed:28709897] |
| Molecular Neurobiology | Neuroprotective Effect of Nanodiamond in Alzheimer’s Disease Rat Model: a Pivotal Role for Modulating NF-κB and STAT3 Signaling[pubmed:26897372] |
| Toxicology and Environmental Health Sciences | Potentiation of Apoptosis in Rat Striatum Exposed to Endosulfan and the Role of Quercetin[10.1007/s13530-017-0325-1] |
| Biomedicine & Pharmacotherapy | Cardioprotective effect of the xanthones from Gentianella acuta against myocardial ischemia/reperfusion injury in isolated rat heart[pubmed:28686977] |
| Scientific Research | Association of Bax and Bcl-2 Functional Polymorphisms and Protein Levels with Posttraumatic Stress Disorder[paperID:82598] |
| Biomaterials | Structural optimization and additional targets identification of antisense oligonucleotide G3139 encapsulated in a neutral cytidinyl-lipid combined with a cationic lipid?…[Pubmed: 30660994] |
| PeerJ. | Taxifolin protects rat against myocardial ischemia/reperfusion injury by modulating the mitochondrial apoptosis pathway[Pubmed: 30723634] |
| 博士論文 | INSTITUTO DE CIENCIAS BáSICAS Y PRECLíNICAS “VICTORIA DE GIRóN” DEPARTAMENTO DE HISTOLOGíA[] |
| pharmacological research | Neuroprotection in non-transgenic and transgenic mouse models of Alzheimer's disease by positive modulation of σ1 receptors[Pubmed: 31048034] |
| Int Immunopharmacol | Metallothionein-1 is associated with osteoarthritis disease activity and suppresses proinflammatory cytokines production in synovial cells[Pubmed: 31465913] |
| Experimental Cell Research | LncRNA SNHG3 promotes clear cell renal cell carcinoma proliferation and migration by upregulating TOP2A[Pubmed: 31505165] |
| Toxicology | LCZ696 (sacubitril/valsartan) protects against cyclophosphamide-induced testicular toxicity in rats: Role of neprilysin inhibition and lncRNA TUG1 in ameliorating …[Pubmed: 32197949] |
| Odontology | Effects of different pulp-capping materials on cell death signaling pathways of lipoteichoic acid-stimulated human dental pulp stem cells[Pubmed: 33206337] |
| Environ Sci Pollut Res Int | Potentiation of the apoptotic signaling pathway in both the striatum and hippocampus and neurobehavioral impairment in rats exposed chronically to a low? dose of?…[Pubmed: 32915453] |
| Drug Chem Toxicol | Alogliptin attenuates cyclophosphamide-induced nephrotoxicity: a novel therapeutic approach through modulating MAP3K/JNK/SMAD3 signaling cascade[Pubmed: 32869669] |
| Iranian Journal of phamaceutical research | Potential anti-tumor activity of kefir-induced juglone and resveratrol fractions against Ehrlich ascites carcinoma-bearing BALB/c mice[] |
| ACS APPLIED BIO MATERIALS | Curcumin loaded nanostructure hybrid lipid capsules for co-eradication of breast cancer and cancer stem cells with enhanced anticancer efficacy[] |
| Folia Biologica | Effect of Graviola (Annona Muricata l.) and Ginger (Zingiber Officinale Roscoe) on Diabetes Mellitus Induced in Male Wistar Albino Rats[] |
| Current Nutrition & Food Science | The Effect of Sodium Metabisulphite on Apoptosis in the Experimental Model of Parkinson's Disease[] |
| Life Sci | Cilostazol mitigates mesenteric ischemia/reperfusion-induced lung lesion: Contribution of PPAR-|?, NF-|êB, and STAT3 crosstalk[33310046] |
| J Biochem Mol Toxicol | Potential effect of adrenomedullin on metabolic and endocrinal dysfunctions in the experimentally induced polycystic ovary: Targeting implication of endoplasmic ?-[33491863] |
| Drug Des Devel Ther | Magnesium Isoglycyrrhizinate Alleviates Arsenic Trioxide-Induced Cardiotoxicity: Contribution of Nrf2 and TLR4/NF-|êB Signaling Pathway[33603344] |
| Crystals | Potential Therapeutic Effects of New Ruthenium (III) Complex with Quercetin: Characterization, Structure, Gene Regulation, and Antitumor and Anti-Inflammatory Studies (RuIII/Q Novel Complex Is a Potent Immunoprotective Agent)[] |
| BIOTECHNOLOGIES | Expression of Apoptotic Markers Bcl-2 and Bax in the Vascular Wall[] |
| Pharmacol Res Perspect | [8]‐Gingerol exerts anti‐myocardial ischemic effects in rats via modulation of the MAPK signaling pathway and L‐type Ca2+ channels[34390539] |
| Ecotoxicol Environ Saf | Lycopene attenuates zearalenone-induced oxidative damage of piglet sertoli cells through the nuclear factor erythroid-2 related factor signaling pathway[34482067] |
| Biomed Pharmacother | Allicin ameliorates renal ischemia/reperfusion injury via inhibition of oxidative stress and inflammation in rats[34426252] |
| Environ Sci Pollut Res Int | Galangin mitigates oxidative stress, inflammation, and apoptosis in a rat model of methotrexate hepatotoxicity[34729716] |
| Sci Rep | Curcumin derivative ST09 modulates the miR-199a-5p/DDR1 axis and regulates proliferation and migration in ovarian cancer cells[34837026] |
| J Ethnopharmacol | Isolation and characterization of anti-inflammatory and anti-proliferative compound, for B-cell Non-Hodgkin lymphoma, from Nyctanthes arbor-tristis Linn.[Pubmed:35398498] |
| Life Sci | Selenium nanoparticles overcomes sorafenib resistance in thioacetamide induced hepatocellular carcinoma in rats by modulation of mTOR, NF-κB pathways and?…[Pubmed:35640776] |
| Life Sci | Piracetam attenuates cyclophosphamide-induced hepatotoxicity in rats: Amelioration of necroptosis, pyroptosis and caspase-dependent apoptosis[Pubmed:35636581] |
| Antioxidants (Basel) | Anti-Inflammatory, Anti-Apoptotic, and Antioxidant Roles of Honey, Royal Jelly, and Propolis in Suppressing Nephrotoxicity Induced by Doxorubicin in Male Albino?…[Pubmed:35624893] |
| Experimental and Therapeutic Medicine | Nephroprotective effect of magnesium isoglycyrrhizinate against arsenic trioxide?induced acute kidney damage in mice[Pubmed:35317438] |
| Biointerface Research in Applied Chemistry | Beetroot Improves the Therapeutic Efficacy of Bone Marrow-Derived Mesenchymal Stem Cells in Preventing Cisplatin Induced Nephrotoxicity in Male Rats[] |