雌激素受體α(ERa)重組蛋白
Recombinant Estrogen Receptor Alpha (ERa)
ER-A1; ER; ESR; ESR1; ESRA; NR3A1; NR3-A1; Estrogen Receptor 1; Nuclear Receptor Subfamily 3,Group A,Member 1
- 編號(hào)RPB050Hu01
- 物種Homo sapiens (Human，人)相同的名稱，不同的物種。
- 來(lái)源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
- 亞細(xì)胞定位細(xì)胞膜, 細(xì)胞核, 細(xì)胞質(zhì)
- 預(yù)測(cè)分子量33.4kDa
- 實(shí)際分子量33kDa(差異分析請(qǐng)參閱說(shuō)明書)
- 片段與標(biāo)簽Ser178~Met438 with N-terminal His Tag
- 緩沖液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- 性狀凍干粉
- 純度> 90%
- 等電點(diǎn)9.0
- 應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請(qǐng)參見活性蛋白。 - 下載英文說(shuō)明書 中文說(shuō)明書
- 規(guī)格10μg50μg200μg1mg5mg
- 價(jià)格¥ 1080¥ 2700¥ 5400¥ 16200¥ 40500
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
Figure . Gene Sequencing (extract)
Figure. SDS-PAGE
通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過(guò)一個(gè)月，-80°C不超過(guò)12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號(hào) | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPB050Hu02 | 雌激素受體α(ERa)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB050Hu01 | 雌激素受體α(ERa)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB050Hu01 | 雌激素受體α(ERa)多克隆抗體 | WB;ICC/IF |
| LAB050Hu71 | 雌激素受體α(ERa)多克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
| MAB050Hu22 | 雌激素受體α(ERa)單克隆抗體 | WB; IHC; ICC; IP. |
| SEB050Hu | 雌激素受體α(ERa)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMB050Hu | 雌激素受體α(ERa)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| The Journal of Steroid Biochemistry and Molecular Biology | Neuroprotective action of raloxifene against hypoxia-induced damage in mouse hippocampal cells depends on ERα but not ERβ or GPR30 signalling[Pubmed:24846829] |
| Biochem Biophys Res Commun | Differential expression of estrogen receptor α and β isoforms in multiple and solitary leiomyomas[PubMed: 26529545] |
| Journal of Environmental Sciences | Bisphenol A exposure alters release of immune and developmental modulators and expression of estrogen receptors in human fetal lung fibroblasts[science:S1001074216300924] |
| cellular microbiology | Influenza A virus NS1 protein-induced JNK activation and apoptosis are not functionally linked.[pubmed:28076660] |
| Journal of Steroid Biochemistry and Molecular Biology | Depressive-like effect of prenatal exposure to DDT involves global DNA hypomethylation and impairment of GPER1/ESR1 protein levels but not ESR2 and AHR/ARNT signaling[pubmed:28263910] |
| Cellular?Physiology and Biochemistry | Antiestrogenic Activity of the Xi-Huang Formula for Breast Cancer by Targeting the Estrogen Receptor α[Pubmed:29975948] |
| Carleton University Research Virtual Environment | In Vitro Study of Mechanisms Underlying the Developmental Effects of Bisphenol A Using Human Fetal Lung Fibroblasts[] |
| Clinical Breast Cancer | Vitamin D receptor in breast cancer tissues and its relation to estrogen receptor alpha (ER-a) gene expression and serum 25-hydroxyvitamin D levels in Egyptian?[Doi: 10.1016/j.clbc.2018.12.019] |
| Journal of geriatric?psychiatry?and neurology | ERα Gene Promoter Methylation in Cognitive Function and Quality of Life of Patients With Alzheimer Disease[Pubmed: 30947592] |
| mBio | The Effector Domain of the Influenza A Virus Nonstructural Protein NS1 Triggers Host Shutoff by Mediating Inhibition and Global Deregulation of Host Transcription?…[34488451] |
| Cardiometry | Modifying effect of obesity on the content of sex hormones and their receptors in endometrial adenocarcinoma and its surrounding tissue[] |