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胰島素降解酶(IDE)單克隆抗體

Monoclonal Antibody to Insulin Degrading Enzyme (IDE)

Insulysin; Insulin Protease; Abeta-degrading protease; Insulinase

  • 胰島素降解酶(IDE)單克隆抗體產(chǎn)品包裝(模擬)
  • 胰島素降解酶(IDE)單克隆抗體產(chǎn)品包裝(模擬)
  • MAB897Hu21.jpgWestern Blot; Sample: K562 cell lysate Primary Ab: 0.5μg/ml Mouse Anti-Human IDE Antibody Second Ab: 0.2μg/mL HRP-Linked Caprine Anti-Mouse IgG Polyclonal Antibody (Catalog: SAA544Mu19)
  • Certificate通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

特異性

該抗體是針對IDE的小鼠單克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別IDE。

用法

Western blotting: 0.5-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.

儲存

經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定,具體方法如下:在37°C孵育48小時,沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi),在適當(dāng)?shù)臈l件下存儲,損失率低于5%。

贈品

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編號適用物種:Homo sapiens (Human,人)應(yīng)用(僅供研究使用,不用于臨床診斷!)
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參考文獻(xiàn)

雜志參考文獻(xiàn)
J NeurochemReduction[PubMed: 26442993]
African Journal of Pharmacy and Pharmacology Peptide hydroxamate derivatives as regulators for insulin receptor signaling and its degradation by zinc metalloprotease in diabetic rats[article-full-text-pdf]
Biomedicine & PharmacotherapyVitamin?D3?intake?as?regulator?of?insulin?degrading?enzyme?and?insulin?receptor?phosphorylationin?diabetic?rats.[pubmed:27930980]
Biological Trace Element ResearchNigella sativa Oil and Chromium Picolinate Ameliorate Fructose-Induced Hyperinsulinemia by Enhancing Insulin Signaling and Suppressing Insulin-Degrading Enzyme in Male Rats[10.1007/s12011-017-1167-z]
NeuroscienceThe Protective Effects of IGF-I against β-Amyloid-related Downregulation of Hippocampal Somatostatinergic System Involve Activation of Akt and Protein Kinase A[Pubmed:29406271]