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過(guò)氧化物酶體增殖物激活受體γ輔激活因子1α(PPARgC1a)單克隆抗體

Monoclonal Antibody to Peroxisome Proliferator Activated Receptor Gamma Coactivator 1 Alpha (PPARgC1a)

LEM6; PGC-1(alpha); PGC-1v; PGC1; PGC1A; PPARGC1; Ligand effect modulator 6

  • 過(guò)氧化物酶體增殖物激活受體γ輔激活因子1α(PPARgC1a)單克隆抗體產(chǎn)品包裝(模擬)
  • 過(guò)氧化物酶體增殖物激活受體γ輔激活因子1α(PPARgC1a)單克隆抗體產(chǎn)品包裝(模擬)
  • Certificate通過(guò)ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

特異性

該抗體是針對(duì)PPARgC1a的小鼠單克隆抗體。在免疫組織化學(xué)染色和免疫印跡實(shí)驗(yàn)中能識(shí)別PPARgC1a。

用法

免疫印跡:0.2-2μg/mL;1:500-5000
免疫組織化學(xué):5-20μg/mL;1:50-200
免疫細(xì)胞化學(xué):5-20μg/mL;1:50-200
最佳稀釋倍數(shù)最終由用戶決定。

儲(chǔ)存

經(jīng)常使用則4°C保存。-20°C保存不超過(guò)兩年。避免反復(fù)凍融。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定,具體方法如下:在37°C孵育48小時(shí),沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi),在適當(dāng)?shù)臈l件下存儲(chǔ),損失率低于5%。

贈(zèng)品

參考文獻(xiàn)

雜志參考文獻(xiàn)
Coronary Artery DiseaseImpaired myocardium energetics associated with the risk for new-onset atrial fibrillation after isolated coronary artery bypass graft surgery[Pubmed: 24463787]
Molecular and cellular biochemistrySkeletal muscle mitochondrial dysfunction precedes right ventricular impairment in experimental pulmonary hypertension[Pubmed: 23099843]
Diabetes. Inorganic nitrate promotes the browning of white adipose tissue through the nitrate-nitrite-nitric oxide pathway[Pubmed:25249574]
PsychoneuroendocrinologyMaternal stress predicts altered biogenesis and the profile of mitochondrial proteins in the frontal cortex and hippocampus of adult offspring rats[PubMed: 26143539]
Biochemistry (Moscow) Supplement Series B: Biomedical ChemistryThe level of circulating PGC1α in cardiovascular diseases[Article: 10.1134]
Neuroscience LettersUnlike PPARgamma, neither other PPARs nor PGC-1alpha is elevated in the cerebrospinal fluid of patients with multiple sclerosis[pubmed:28483651]
The American Journal of the Medical SciencesSerum peroxisome proliferator-activated receptor gamma coactivator-1α related to myocardial energy expenditure in patients with chronic heart failure[Doi: 10.1016/j.amjms.2018.12.002]
Brain ResearchThe effect of antecedent-conditioning high-intensity interval training on BDNF regulation through PGC-1α pathway following cerebral ischemia[Pubmed: 31866362]
Food & FunctionUbiquinol supplementation modulates energy metabolism and bone turnover during high intensity exercise[Pubmed: 32797125]
Brown and beige adipose tissue regulate systemic metabolism to resist diet-induced obesity through metabolite signals in an inter-organ signaling axis[]
CLINICAL NUTRITIONLong lasting protective EFFECTS of early L-ARGININE TREAMENT on ENDOTHELIUM in an in Vitro STUDY[33743287]
Nature CommunicationsBrown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis[33772024]