神經(jīng)調(diào)節(jié)素1(NRG1)重組蛋白
Recombinant Neuregulin 1 (NRG1)
ARIA; GGF; HGL; HRG; HRGA; NDF; SMDF; Acetylcholine receptor-inducing activity; Glial growth factor; Heregulin; Neu differentiation factor; Sensory and motor neuron-derived factor
- 編號(hào)RPB866Ra02
- 物種Rattus norvegicus (Rat,大鼠)相同的名稱,不同的物種。
- 來(lái)源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測(cè)定)
- 亞細(xì)胞定位細(xì)胞膜, 分泌
- 預(yù)測(cè)分子量18.6kDa
- 實(shí)際分子量19kDa(差異分析請(qǐng)參閱說(shuō)明書)
- 片段與標(biāo)簽Ser328~Lys486 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液(pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300)
- 性狀凍干粉
- 純度> 95%
- 等電點(diǎn)7.3
- 應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白,請(qǐng)參見(jiàn)活性蛋白。 - 下載英文說(shuō)明書 中文說(shuō)明書
- 規(guī)格10μg50μg200μg1mg5mg
- 價(jià)格¥ 864 ¥ 2160¥ 4320¥ 12960¥ 32400
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序列

用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過(guò)一個(gè)月,-80°C不超過(guò)12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定,具體方法如下:在37°C孵育48小時(shí),沒(méi)有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi),在適當(dāng)?shù)臈l件下存儲(chǔ),損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
編號(hào) | 適用物種:Rattus norvegicus (Rat,大鼠) | 應(yīng)用(僅供研究使用,不用于臨床診斷!) |
RPB866Ra01 | 神經(jīng)調(diào)節(jié)素1(NRG1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB866Ra02 | 神經(jīng)調(diào)節(jié)素1(NRG1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB866Ra03 | 神經(jīng)調(diào)節(jié)素1(NRG1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
RPB866Ra04 | 神經(jīng)調(diào)節(jié)素1(NRG1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
PAB866Ra02 | 神經(jīng)調(diào)節(jié)素1(NRG1)多克隆抗體 | WB; IHC; ICC; IP. |
PAB866Ra03 | 神經(jīng)調(diào)節(jié)素1(NRG1)多克隆抗體 | WB; IHC; ICC; IP. |
PAB866Ra01 | 神經(jīng)調(diào)節(jié)素1(NRG1)多克隆抗體 | WB; IHC; ICC; IP. |
PAB866Ra04 | 神經(jīng)調(diào)節(jié)素1(NRG1)多克隆抗體 | WB,IHC |
LAB866Ra71 | 神經(jīng)調(diào)節(jié)素1(NRG1)多克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
SEB866Ra | 神經(jīng)調(diào)節(jié)素1(NRG1)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
WEB866Ra | 神經(jīng)調(diào)節(jié)素1(NRG1)檢測(cè)試劑盒(酶聯(lián)免疫吸附試驗(yàn)法,寬范圍) | Enzyme-linked immunosorbent assay for Antigen Detection. |
LMB866Ra | 神經(jīng)調(diào)節(jié)素1(NRG1)等多因子檢測(cè)試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
雜志 | 參考文獻(xiàn) |
Neuroscience Letter | Therapeutic effect of co-transplantation of neuregulin 1-transfected-Schwann cells and bone marrow stromal cells on spinal cord hemisection syndrom[Cyagen: source] |
PLoS One. | ADAM17 Silencing in Mouse Colon Carcinoma Cells: The Effect on Tumoricidal Cytokines and Angiogenesis[PubMed: PMC3519469] |
The Journal of Clinical Investigation | Cerebrospinal fluid–based kinetic biomarkers of axonal transport in monitoring neurodegeneration[PubMed: PMC3428100] |
Physiol Behav | Dysregulation of Neuregulin-1/ErbB signaling in the prefrontal cortex and hippocampus of rats exposed to chronic unpredictable mild stress[PubMed: 26626816] |
J Toxicol Sci.? | Effects of prolonged antipsychotic administration on neureCavia (Guinea pig )lin-1/ErbB signaling in rat prefrontal cortex and myocardium: implications for the therapeutic action and cardiac adverse effect.[Pubmed:26961615] |
journal of cellular and molecular medicine | Qiliqiangxin protects against anoxic injury in cardiac microvascular endothelial cells via NRG-1/ErbB-PI3K/Akt/mTOR pathway.[pubmed:28271613] |
Transl Psychiatry. | Ablation of neuropsin-neuregulin 1 signaling imbalances ErbB4 inhibitory networks and disrupts hippocampal gamma oscillation.[pubmed:28267150] |
Human?Molecular?Genetics | A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas[Pubmed: 30335132] |
Aging (Albany NY) | Jinmaitong ameliorates diabetic peripheral neuropathy in streptozotocin-induced diabetic rats by modulating gut microbiota and neuregulin[Pubmed: 32920546] |