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淀粉樣蛋白β1-40(Ab1-40)多克隆抗體

Polyclonal Antibody to Amyloid Beta Peptide 1-40 (Ab1-40)

  • 淀粉樣蛋白β1-40(Ab1-40)多克隆抗體產(chǎn)品包裝(模擬)
  • 淀粉樣蛋白β1-40(Ab1-40)多克隆抗體產(chǎn)品包裝(模擬)
  • 淀粉樣蛋白β1-40(Ab1-40)多克隆抗體DAB staining on IHC-P;
    Sample: Porcine Cerebrum Tissue
    Primary Ab: 10μg/ml Rabbit Anti-Multi-species Ab1-40 Antibody
    Control: Used PBS instead of primary antibody
    Second Ab: 2μg/ml HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody
    (Catalog: SAA544Rb19)
  • Certificate通過ISO 9001、ISO 13485質(zhì)量體系認證

特異性

該抗體是針對Ab1-40的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別Ab1-40。

用法

Western blotting: 0.01-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Optimal working dilutions must be determined by end user.

儲存

經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定,具體方法如下:在37°C孵育48小時,沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi),在適當(dāng)?shù)臈l件下存儲,損失率低于5%。

贈品

相關(guān)產(chǎn)品

編號適用物種:應(yīng)用(僅供研究使用,不用于臨床診斷!)
PAA864Mi01淀粉樣蛋白β1-40(Ab1-40)多克隆抗體WB; IHC; ICC; IP.

參考文獻

雜志參考文獻
PLoS OneMetabolites of Cerebellar Neurons and Hippocampal Neurons Play Opposite Roles in Pathogenesis of Alzheimer's Disease[PubMed: PMC2677455]
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Electromagnetic Biology and MedicineEffect of 900 MHz Radio Frequency Radiation on Beta Amyloid Protein, Protein Carbonyl, and Malondialdehyde in the Brain[Informa: 15368378.2011.624654]
Electromagnetic Biology and MedicineDo 100- and 500-μT ELF magnetic fields alter beta-amyloid protein, protein carbonyl and malondialdehyde in rat brains?[PubMed: 23324065]
Indian Journal of Experimental BiologyIntranasal administration of insulin lowers amyloid-levels in rat model of diabetes.[PubMed: 22279939]
European Journal of PharmacologyThe γ-secretase inhibitor 2-[(1R)-1-[(4-chlorophenyl)sulfonyl](2,5-difluorophenyl) amino]ethyl-5-fluorobenzenebutanoic acid (BMS-299897) alleviates Aβ1-42 seeding and short-term memory deficits in the Aβ25-35 mouse model of Alzheimer's disease.[ScienceDirect: S0014299912009028]
NeuropsychopharmacologyBlockade of Tau Hyperphosphorylation and Aβ1–42 Generation by the Aminotetrahydrofuran Derivative ANAVEX2-73, a Mixed Muscarinic and σ1 Receptor Agonist, in a Nontransgenic Mouse Model of Alzheimer’s Disease[Pubmed: 23493042]
世界科技研究與發(fā)展(World Sci-tech R & D)慢病毒介導(dǎo)的CBS基因過表達對原代皮質(zhì)神經(jīng)元[Globesci:Source]
Neurochemical researchEffects of Aluminium on β-Amyloid (1–42) and Secretases (APP-Cleaving Enzymes) in Rat Brain[Pubmed:24792732]
Neurochem IntGeniposide attenuates insulin-deficiency-induced acceleration of β-amyloidosis in an APP/PS1 transgenic model of Alzheimer's disease[PubMed: 25882165]
Journal of Alzheimer’s Parkinsonism & DementiaThe Potential Effect of Epigallocatechin-3-Gallate alone or in Combination with Vitamin E and Selenium on Alzheimer's Disease Induced by Aluminum in Rats[open-access:]
Am J Alzheimers Dis Other Demen.Tong Luo Jiu Nao, a Chinese Medicine Formula, Reduces Inflammatory Stress in a Mouse Model of Alzheimer's Disease[Pubmed:26993489]
Scientific ReportsNorovirus P particle-based active Aβ immunotherapy elicits sufficient immunogenicity and improves cognitive capacity in a mouse model of Alzheimer’s disease[articles:srep41041.ris]
Journal?of?Nutritional?BiochemistryMechanisms of DHA-enriched phospholipids in improving cognitive deficits in aged SAMP8 mice with high-fat diet[Pubmed:29986309]
Journal of Agricultural and?Food?ChemistryEffects of Astaxanthin and Docosahexaenoic-Acid-Acylated Astaxanthin on Alzheimer's Disease in APP/PS1 Double-Transgenic Mice[Pubmed:29695154]
NeurotoxicologyAmelioration by nitric oxide (NO) mimetics on neurobehavioral and biochemical changes in experimental model of Alzheimer's disease in rats[Pubmed:29522778]
OncotargetDeletion of plasma Phospholipid Transfer Protein (PLTP) increases microglial phagocytosis and reduces cerebral amyloid-β deposition in the J20 mouse?…[Pubmed:29731975]
Experimental?and?Therapeutic?MedicineEllagic acid ameliorates learning and memory impairment in APP/PS1 transgenic mice via inhibition of β?amyloid production and tau hyperphosphorylation[Doi: 10.3892/etm.2018.6860]
非編碼RNA miR-137 調(diào)控tau 蛋白磷酸化和L 型鈣離子通道CACNA1C 參與阿爾茨海默病的發(fā)生[]
Neurotoxicity ResearchEffect of Aluminum-Maltolate on the Content of Aβ Protein and the Expression of ApoER2, VLDLRs, and LRP1 in PC12-ApoE4 Cells[Pubmed: 30649678]
PLoS OneObstructive sleep apnea may increase the risk of Alzheimer's disease[Pubmed: 31487291]
Frontiers in Aging NeurosciencePrevention of Early Alzheimer's Disease by Erinacine A-Enriched Hericium erinaceus Mycelia Pilot Double-Blind Placebo-Controlled Study[Pubmed: 32581767]
PYRIMIDINE-4H-1OH DERIVATIVES RESTORE MITOCHONDRIAL FUNCTION IN EXPERIMENTAL CHRONIC TRAUMATIC ENCEPHALOPATHY[]
Pharmacognosy MagazineMahanimbine-induced neuroprotection via cholinergic system and attenuated amyloidogenesis as well as neuroinflammation in lipopolysaccharides-induced?…[]
Neurochem IntLovastatin attenuates sevoflurane-induced cognitive disorder in aged rats via reducing A|? accumulation[34048842]
Brain Res BulImmunization with A|?3-10-KLH vaccine improves cognitive function and ameliorates mitochondrial dysfunction and reduces Alzheimer's disease-like pathology in Tg ?-[34044034]