表皮調(diào)節(jié)素(EREG)多克隆抗體
Polyclonal Antibody to Epiregulin (EREG)
EPR; ER; Proepiregulin
- 編號PAB945Hu02
- 物種Homo sapiens (Human，人)相同的名稱，不同的物種。
- 來源多抗制備
- 宿主兔
- 效價(jià)-
- Ig類型IgG
- 純化方式抗原特異性親和純化
- 標(biāo)記物無標(biāo)記物
- 免疫原RPB945Hu02-表皮調(diào)節(jié)素(EREG)重組蛋白
- 緩沖液成份0.01M 磷酸鹽緩沖液（pH7.4，containing 0.05% Proclin-300，50% glycerol）
- 性狀液體
- 濃度0.5mg/mL
- 且適物種Sus scrofa; Porcine (Pig，豬)
- 應(yīng)用WB
如果抗體需用于流式細(xì)胞術(shù)，請參見流式抗體。 - 下載英文說明書 中文說明書
- 規(guī)格20μl100μl200μl1ml10ml
- 價(jià)格¥ 617¥ 1441¥ 2058¥ 5145¥ 20580
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
Western Blot; Sample: Porcine Tongue lysate Primary Ab: 0.05μg/ml Rabbit Anti-Human EREG Antibody Second Ab: 0.2μg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19
通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
特異性
該抗體是針對EREG的兔多克隆抗體。在免疫組織化學(xué)染色和免疫印跡實(shí)驗(yàn)中能識別EREG。
用法
Western blotting: 0.01-2μg/mL
Optimal working dilutions must be determined by end user.
儲存
經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
贈(zèng)品
增值服務(wù)
抗體標(biāo)記定制服務(wù)
Protein-A/G純化柱
細(xì)胞和組織染色液
抗體陽性對照品
組織/切片定制服務(wù)
磷酸化抗體定制服務(wù)
免疫印跡(WB)實(shí)驗(yàn)服務(wù)
免疫組織化學(xué)(IHC)實(shí)驗(yàn)服務(wù)
免疫細(xì)胞化學(xué)(ICC)實(shí)驗(yàn)服務(wù)
流式細(xì)胞術(shù)(FCM)實(shí)驗(yàn)服務(wù)
免疫沉淀(IP)實(shí)驗(yàn)服務(wù)
免疫熒光(IF)實(shí)驗(yàn)服務(wù)
緩沖液
DAB顯色試劑盒
SABC試劑盒
長臂生物素標(biāo)記試劑盒
實(shí)時(shí)熒光定量PCR實(shí)驗(yàn)服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPB945Hu02 | 表皮調(diào)節(jié)素(EREG)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB945Hu04 | 表皮調(diào)節(jié)素(EREG)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB945Hu01 | 表皮調(diào)節(jié)素(EREG)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPB945Hu03 | 表皮調(diào)節(jié)素(EREG)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAB945Hu02 | 表皮調(diào)節(jié)素(EREG)多克隆抗體 | WB |
| PAB945Hu01 | 表皮調(diào)節(jié)素(EREG)多克隆抗體 | WB |
| PAB945Hu04 | 表皮調(diào)節(jié)素(EREG)多克隆抗體 | WB; IHC; ICC; IP. |
| MAB945Hu22 | 表皮調(diào)節(jié)素(EREG)單克隆抗體 | WB; IHC; ICC; IP. |
| SEB945Hu | 表皮調(diào)節(jié)素(EREG)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| SCB945Hu | 表皮調(diào)節(jié)素(EREG)檢測試劑盒(化學(xué)發(fā)光免疫分析法) | Chemiluminescent immunoassay for Antigen Detection. |
| LMB945Hu | 表皮調(diào)節(jié)素(EREG)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| British Journal of Cancer | Cross-suppression of EGFR ligands amphiregulin and epiregulin and de-repression of FGFR3 signalling contribute to cetuximab resistance in wild-type KRAS tumour cells[Nature: 2012103] |
| J Pharmacol Exp Ther. | Aryl hydrocarbon receptor antagonism attenuates growth factor expression, proliferation, and migration in fibroblast-like synoviocytes from patients with rheumatoid arthritis.[Pubmed: 24309559] |
| Molecular Carcinogenesis | The Ah receptor regulates growth factor expression in head and neck squamous cell carcinoma cell lines[Pubmed:23625689] |
| Am J Physiol Gastrointest Liver Physiol. | Epiregulin promotes the emergence and proliferation of adult liver progenitor cells.[Pubmed:24812054] |
| European Review for Medical and Pharmacological Sciences | Epiregulin-loaded PLGA nanoparticles increase human keratinocytes proliferation: preliminary data[pubmed:27383296] |
| Oncotarget | Overexpression of a functional calcium-sensing receptor dramatically increases osteolytic potential of MDA-MB-231 cells in a mouse model of bone metastasis through epiregulin-mediated osteoprotegerin downregulation[PMC5593575] |
| American journal of respiratory cell and molecular biology | Potential Involvement of the Epidermal Growth Factor Receptor Ligand Epiregulin and Matrix Metalloproteinase-1 in Pathogenesis of Chronic Rhinosinusitis[pubmed:28398769] |
| International?Journal?of?Cancer | Epigenetic regulation of Amphiregulin and Epiregulin in colorectal cancer[Pubmed: 30252132] |
| Epiregulin is released from intervertebral disks and induces spontaneous activity in pain pathways[Doi: 10.1097/PR9.0000000000000718] | |
| Cell proliferation | Epiregulin enhances odontoblastic differentiation of dental pulp stem cells via activating MAPK signalling pathway[Pubmed: 31454111] |
| International Journal of Molecular Sciences | Promising Therapeutic Efficacy of GC1118, an Anti-EGFR Antibody, against KRAS Mutation-Driven Colorectal Cancer Patient-Derived Xenografts[Pubmed: 31771279] |
| Neoplasia | Patient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine[Pubmed: 33212364] |
| Reprod Sci | Compromised Cumulus-Oocyte Complex Matrix Organization and Expansion in Women with PCOS[34748173] |
| Tissue and Cell | MiR-192-5p suppresses M1 macrophage polarization via epiregulin (EREG) downregulation in gouty arthritis[34715618] |