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表皮生長因子受體(EGFR)重組抗體

Recombinant Antibody to Epidermal Growth Factor Receptor (EGFR)

ErbB-1; ErbB1; ER1; ERB-B1; MENA; HER1; Erythroblastic Leukemia Viral(v-Erb-B)oncogene Homolog,Avian; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1

  • 表皮生長因子受體(EGFR)重組抗體產(chǎn)品包裝(模擬)
  • 表皮生長因子受體(EGFR)重組抗體產(chǎn)品包裝(模擬)
  • 表皮生長因子受體(EGFR)重組抗體Human Hela cell line was?stained?with?5-10μg/ml?mouse Anti-human EGFR Recombinant Antibodies (Catalog # RAA757Hu21, red histogram)?or?Isotype?control?antibody?(Catalog # IS067-Mu03, green histogram),?followed?by?1μg/ml?FITC-conjugated Anti-mouse IgG Secondary Antibody (Catalog # SAA544Mu18).
  • 表皮生長因子受體(EGFR)重組抗體Human peripheral blood lymphocytes were stained with 0.2μg/ml mouse Anti-human EGFR Recombinant Antibody (Catalog RAA757Hu21, red histogram) or Isotype control antibody (Catalog IS067-Mu03, green histogram), followed by 1μg/ml FITC-conjugated Anti-mouse IgG Secondary Antibody (Catalog SAA544Mu18).
  • Certificate通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

特異性

該抗體是針對EGFR的小鼠單克隆抗體。在免疫組織化學(xué)染色和免疫印跡實驗中能識別EGFR。

用法

Western blotting: 0.2-2μg/mL;
Immunohistochemistry: 5-20μg/mL;
Immunocytochemistry: 5-20μg/mL;
Flow cytometry:10μg/ml;
Optimal working dilutions must be determined by end user.

儲存

經(jīng)常使用則4°C保存。-20°C保存不超過兩年。避免反復(fù)凍融。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定,具體方法如下:在37°C孵育48小時,沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi),在適當(dāng)?shù)臈l件下存儲,損失率低于5%。

贈品

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參考文獻(xiàn)

雜志參考文獻(xiàn)
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J Cent Nerv Syst Dis.?Increased Epidermal Growth Factor Receptor (EGFR) Associated with Hepatocyte Growth Factor (HGF) and Symptom Severity in Children with Autism …[Pubmed:25249767]
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Cell Death Dis.?LINC01225 promotes occurrence and metastasis of hepatocellular carcinoma in an epidermal growth factor receptor-dependent pathway[Pubmed:26938303]
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TalantaEGFR detection in extracellular vesicles of breast cancer patients through immunosensor based on silica-chitosan nanoplatform[Doi: 10.1016/j.talanta.2018.10.016]
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Journal of?enzyme?inhibition and medicinal chemistryNovel thienopyrimidine derivatives as dual EGFR and VEGFR-2 inhibitors: design, synthesis, anticancer activity and effect on cell cycle profile[Pubmed: 30919701]
Bioorganic ChemistryDesign and synthesis of new benzoxazole/benzothiazole-phthalimide hybrids as antitumor-apoptotic agents[]
Bioorganic ChemistrySynthesis and anticancer activity of bis-benzo [d][1, 3] dioxol-5-yl thiourea derivatives with molecular docking study[Pubmed: 31288134]
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NeoplasiaPatient-derived xenograft (PDX) models of colorectal carcinoma (CRC) as a platform for chemosensitivity and biomarker analysis in personalized medicine[Pubmed: 33212364]
Association between Serum Epidermal Growth Factor Receptor and Cyclooxygenase-2 Levels in Patients with Non-small Cell Carcinoma of Lung[]
Synthesis, EGFR-TK inhibition and anticancer activity of new quinoxaline derivatives[]
IMMUNOLOGIC RESEARCHHumoral immune response to epidermal growth factor receptor in lung cancer[33495907]
European Journal of Medicinal ChemistryPyrazolo[3,4-d]pyrimidine-based dual EGFR T790M/HER2 inhibitors: Design, synthesis, structure¨Cactivity relationship and biological activity as potential antitumor and anticonvulsant agents[33545637]
Journal of Molecular StructureDesign, synthesis, antiproliferative evaluation, and molecular docking study of new quinoxaline derivatives as apoptotic inducers and EGFR inhibitors[]
ACS Appl Mater InterfacesEmitter–Quencher Pair of Single Atomic Co Sites and Monolayer Titanium Carbide MXenes for Luminol Chemiluminescent Reactions[34914377]
Bioorganic ChemistryDiscovery of new pyrimido [5, 4-c] quinolines as potential antiproliferative agents with multitarget actions: Rapid synthesis, docking, and ADME studies[Pubmed:35219045]