Ⅳ型膠原α1(COL4a1)重組蛋白
Recombinant Collagen Type IV Alpha 1 (COL4a1)
COL4-A1; Arresten; Collagen Alpha-1(IV)chain
- 編號RPA149Bo01
- 物種Bos taurus; Bovine (Cattle，牛)相同的名稱，不同的物種。
- 來源原核表達
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細胞定位分泌, 細胞外基質(zhì)
- 預測分子量28.6kDa
- 實際分子量29kDa(差異分析請參閱說明書)
- 片段與標簽Gly1445~Thr1669 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 90%
- 等電點8.0
- 應用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載英文說明書 中文說明書
- 規(guī)格10μg50μg200μg1mg5mg
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
Figure . Gene Sequencing (extract)
Figure. SDS-PAGE
通過ISO 9001、ISO 13485質(zhì)量體系認證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當?shù)臈l件下存儲，損失率低于5%。
增值服務
相關產(chǎn)品
| 編號 | 適用物種：Bos taurus; Bovine (Cattle，牛) | 應用(僅供研究使用，不用于臨床診斷！) |
| RPA149Bo01 | Ⅳ型膠原α1(COL4a1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
參考文獻
| 雜志 | 參考文獻 |
| Cancer Research | Peritoneal Dissemination Requires an Sp1-Dependent CXCR4/CXCL12 Signaling Axis and Extracellular Matrixa??Directed Spheroid Formation[Pubmed:26744523] |
| PLoS One | miR-146a regulates glucose induced upregulation of inflammatory cytokines extracellular matrix proteins in the retina and kidney in diabetes[10.1371] |
| Journal of Diabetes & Metabolic Disorders | Endothelin-1 traps potently reduce pathologic markers back to basal levels in an in vitro model of diabetes[] |
| Experimental and Molecular Pathology? | Epitope recognized by anti-glomerular basement membrane (GBM) antibody in a patient with repeated relapse of anti-GBM disease[Pubmed: 30817909] |
| Journal of Diabetes & Metabolic Disorders | In vivo studies demonstrate that endothelin-1 traps are a potential therapy for type I diabetes[] |
| Frontiers in Endocrinology | Curcumin Analogs Reduce Stress and Inflammation Indices in Experimental Models of Diabetes[Pubmed: 31920992] |