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組蛋白H4(H4)重組蛋白

Recombinant Histone H4 (H4)

  • 編號RPA289Mi02
  • 物種Homo sapiens (Human，人), Mus musculus (Mouse，小鼠), Rattus norvegicus (Rat，大鼠), Cavia (Guinea pig ，豚鼠), Rhesus monkey (Simian，恒河猴), Felis catus; Feline (Cat，貓), Canis familiaris; Canine (Dog，犬), Sus scrofa; Porcine (Pig，豬), Bos taurus; Bovine (Cattle，牛), Equus caballus; Equine (Horse，馬)相同的名稱，不同的物種。
  • 來源原核表達(dá)
  • 宿主E.coli
  • 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
  • 亞細(xì)胞定位分泌, 染色體
  • 預(yù)測分子量41.3kDa
  • 實(shí)際分子量42kDa(差異分析請參閱說明書)
  • 片段與標(biāo)簽Ser2~Gly103 with N-terminal His and GST Tag
  • 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
  • 性狀凍干粉
  • 純度> 90%
  • 等電點(diǎn)11.9
  • 應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
    如果需要有生物活性的蛋白，請參見活性蛋白。
  • 下載英文說明書   中文說明書
  • 規(guī)格10μg50μg200μg1mg5mg
  • 價(jià)格¥ 984¥ 2460¥ 4920¥ 14760¥ 36900
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  • 組蛋白H4(H4)重組蛋白產(chǎn)品包裝(模擬)
  • 組蛋白H4(H4)重組蛋白產(chǎn)品包裝(模擬)
  • 組蛋白H4(H4)重組蛋白Figure . Gene Sequencing (extract)
  • RPA289Mi02.jpgFigure. SDS-PAGE
  • Certificate通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證

序列

用法

Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

儲存

避免反復(fù)凍融。2-8°C不超過一個(gè)月，-80°C不超過12個(gè)月。

穩(wěn)定性

熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。

相關(guān)產(chǎn)品

編號適用物種：Homo sapiens (Human，人), Mus musculus (Mouse，小鼠), Rattus norvegicus (Rat，大鼠), Cavia (Guinea pig ，豚鼠), Rhesus monkey (Simian，恒河猴), Felis catus; Feline (Cat，貓), Canis familiaris; Canine (Dog，犬), Sus scrofa; Porcine (Pig，豬), Bos taurus; Bovine (Cattle，牛), Equus caballus; Equine (Horse，馬)應(yīng)用(僅供研究使用，不用于臨床診斷！)
RPA289Mi02組蛋白H4(H4)重組蛋白Positive Control; Immunogen; SDS-PAGE; WB.
RPA289Mi01組蛋白H4(H4)重組蛋白Positive Control; Immunogen; SDS-PAGE; WB.
PAA289Mi02組蛋白H4(H4)多克隆抗體WB; IHC; ICC; IP.
PAA289Mi01組蛋白H4(H4)多克隆抗體WB; IHC; ICC; IP.
SEA289Mi組蛋白H4(H4)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法)Enzyme-linked immunosorbent assay for Antigen Detection.
HEA289Mi組蛋白H4(H4)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法,高敏型)Enzyme-linked immunosorbent assay for Antigen Detection.
LMA289Mi組蛋白H4(H4)等多因子檢測試劑盒(流式熒光發(fā)光法)FLIA Kit for Antigen Detection.

參考文獻(xiàn)

雜志參考文獻(xiàn)
PLoS One. N-Acetyl-Heparin Attenuates Acute Lung Injury Caused by Acid Aspiration Mainly by Antagonizing Histones in Mice[Pubmed:24816808]
Crit Care. Impact of plasma histones in human sepsis and their contribution to cellular injury and inflammation[Pubmed:25260379]
Biomed Res IntA Novel Anti-Histone H2 Monoclonal Antibody, SSV Monoclonal Antibody, Improves Lung Injury and Survival in a Mouse Model of Lipopolysaccharide-Induced Sepsis-Like Syndrome[PubMed: 25649891]
Journal of Viral HepatitisPatients with HBV-related acute-on-chronic liver failure have increased concentrations of extracellular histones aggravating cellular damage and systemic inflammation[pubmed:27660136]
Cell?Death?&?DiseaseDexmedetomidine inhibits astrocyte pyroptosis and subsequently protects the brain in in vitro and in vivo models of sepsis[Pubmed: 30778043]
Respir ResHistone H4 induces heparan sulfate degradation by activating heparanase in chlorine gas-induced acute respiratory distress syndrome[Pubmed:35073921]