高溫需求因子A1(HTRA1)重組蛋白
Recombinant High Temperature Requirement Factor A1 (HTRA1)
HtrA; L56; ORF480; PRSS11; HtrA Serine Peptidase 1; Protease,Serine,11; IGFBP5-Protease; High-temperature requirement A serine peptidase 1
- 編號RPL604Co02
- 物種Escherichia coli(大腸桿菌)相同的名稱，不同的物種。
- 來源原核表達
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細(xì)胞定位細(xì)胞膜
- 預(yù)測分子量15.5kDa
- 實際分子量16kDa(差異分析請參閱說明書)
- 片段與標(biāo)簽Lys304~Lys442 with N-terminal His Tag
- 緩沖液成份磷酸鹽緩沖液（pH7.4，含有 0.01% SKL, 1mM DTT, 5% Trehalose和Proclin300.）
- 性狀凍干粉
- 純度> 97%
- 等電點9.9
- 應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載英文說明書 中文說明書
- 規(guī)格10μg50μg200μg1mg5mg
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
SDS-PAGE圖
通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復(fù)凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Escherichia coli(大腸桿菌) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| RPL604Co02 | 高溫需求因子A1(HTRA1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| RPL604Co01 | 高溫需求因子A1(HTRA1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAL604Co01 | 高溫需求因子A1(HTRA1)多克隆抗體 | WB; IHC; ICC; IP. |
| PAL604Co02 | 高溫需求因子A1(HTRA1)多克隆抗體 | WB |
參考文獻
| 雜志 | 參考文獻 |
| Placenta | Alterations of maternal plasma HTRA1 level in preeclampsia complicated by IUGR[PubMed: 23083999] |
| Placenta | Upregulation of HtrA4 in the placentas of patients with severe pre-eclampsia[PubMed: 22964307] |
| Exp Gerontol | Association of frailty with the serine protease HtrA1 in older adults[Pubmed:27058767] |
| International Journal of?Clinical?and Experimental Pathology | HtrA1 up-regulates expression of MMPs via Erk1/2/Rock-dependent pathways[files:ijcep0069706.pdf] |
| Pregnancy Hypertension | Association between first trimester plasma htra1 level and subsequent preeclampsia: a possible early marker?[] |
| American journal of translational research | HtrA1 upregulates the expression of ADAMTS-5 in HNPCs via the ERK/NF-κB/JNK signaling pathway[Pubmed: 31497227] |
| J Matern Fetal Neonatal Med | First trimester HtrA1 maternal plasma level and spontaneous preterm birth[Pubmed: 32102578] |
| BMC Geriatr | Cross-sectional associations among P3NP, HtrA, Hsp70, Apelin and sarcopenia in Taiwanese population[33743591] |