分泌型卷曲相關(guān)蛋白1(SFRP1)重組蛋白
Recombinant Secreted Frizzled Related Protein 1 (SFRP1)
FRP1; FRP; FRP-1; FrzA; SARP2; Secreted apoptosis-related protein 2
- 編號RPF880Ra01
- 物種Rattus norvegicus (Rat，大鼠)相同的名稱，不同的物種。
- 來源原核表達(dá)
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細(xì)胞定位分泌
- 預(yù)測分子量17.9kDa
- 實(shí)際分子量20kDa(差異分析請參閱說明書)
- 片段與標(biāo)簽Val8~Asp153 with N-terminal His Tag
- 緩沖液成份PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.
- 性狀凍干粉
- 純度> 95%
- 等電點(diǎn)9.1
- 應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載英文說明書 中文說明書
- 規(guī)格10μg50μg200μg1mg5mg
- 價(jià)格¥ 1104¥ 2760¥ 5520¥ 16560¥ 41400
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
Figure. SDS-PAGE
通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲(chǔ)存
避免反復(fù)凍融。2-8°C不超過一個(gè)月，-80°C不超過12個(gè)月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗(yàn)決定，具體方法如下：在37°C孵育48小時(shí)，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲(chǔ)，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Rattus norvegicus (Rat，大鼠) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| APF880Ra01 | 分泌型卷曲相關(guān)蛋白1(SFRP1)活性蛋白 | Cell?culture;?Activity?Assays. |
| RPF880Ra01 | 分泌型卷曲相關(guān)蛋白1(SFRP1)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAF880Ra01 | 分泌型卷曲相關(guān)蛋白1(SFRP1)多克隆抗體 | WB; IHC; ICC; IP. |
| LAF880Ra71 | 分泌型卷曲相關(guān)蛋白1(SFRP1)多克隆抗體(生物素標(biāo)記) | WB; IHC; ICC. |
| MAF880Ra24 | 分泌型卷曲相關(guān)蛋白1(SFRP1)單克隆抗體 | IHC |
| MAF880Ra22 | 分泌型卷曲相關(guān)蛋白1(SFRP1)單克隆抗體 | IHC |
| MAF880Ra25 | 分泌型卷曲相關(guān)蛋白1(SFRP1)單克隆抗體 | IHC |
| MAF880Ra23 | 分泌型卷曲相關(guān)蛋白1(SFRP1)單克隆抗體 | IHC; ICC/IF |
| MAF880Ra21 | 分泌型卷曲相關(guān)蛋白1(SFRP1)單克隆抗體 | WB; IHC; ICC; IP. |
| MAF880Ra27 | 分泌型卷曲相關(guān)蛋白1(SFRP1)單克隆抗體 | IHC |
| SEF880Ra | 分泌型卷曲相關(guān)蛋白1(SFRP1)檢測試劑盒(酶聯(lián)免疫吸附試驗(yàn)法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMF880Ra | 分泌型卷曲相關(guān)蛋白1(SFRP1)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻(xiàn)
| 雜志 | 參考文獻(xiàn) |
| BMC Musculoskeletal Disorders | Biomarkers and cytokines of bone turnover: extensive evaluation in a cohort of patients with ankylosing spondylitis[PubMed: 23025387] |
| Exp Cell Res | Wnt Inhibition is Dysregulated in Gliomas and its Re-Establishment Inhibits Proliferation and Tumor Sphere Formation[PubMed: 26712519] |
| BMC Musculoskeletal Disorders | Correlation?of?blood?bone?turnover?biomarkers?and?Wnt?signaling?antagonists?with AS,?DISH,OPLL, and?OYL.[pubmed:28153008] |
| PloS one | Effects of exercise training on circulating levels of Dickkpof-1 and secreted frizzled-related protein-1 in breast cancer survivors: A pilot single-blind randomized controlled trial.[pubmed:28178355] |
| PLoS One | Effects of exercise training on circulating levels of Dickkpof-1 and secreted frizzled-related protein-1 in breast cancer survivors: A pilot single-blind randomized controlled trial[10.1371] |
| Journal of Experimental & Clinical Cancer Research | PHF21B overexpression promotes cancer stem cell-like traits in prostate cancer cells by activating the Wnt/β-catenin signaling pathway[pubmed:28645312] |
| JBMR Plus | Low serum levels of DKK2 predict incident low‐impact fracture in older women[Doi: 10.1002/jbm4.10179] |
| Nature Communications | Immunological history governs human stem cell memory CD4 heterogeneity via the Wnt signaling pathway[Pubmed: 32041953] |
| acta pharmacologica sinica | sFRP1 protects H9c2 cardiac myoblasts from doxorubicin-induced apoptosis by inhibiting the Wnt/PCP-JNK pathway[Pubmed: 32238888] |