維生素D受體(VDR)重組蛋白
Recombinant Vitamin D Receptor (VDR)
NR1I1; Nuclear Receptor Subfamily 1 Group I Member 1; Calcitriol Receptor; 1,25-dihydroxyvitamin D3 receptor
- 編號RPA475Hu01
- 物種Homo sapiens (Human，人)相同的名稱，不同的物種。
- 來源原核表達
- 宿主E.coli
- 內(nèi)毒素水平<1.0EU/µg(LAL法測定)
- 亞細(xì)胞定位細(xì)胞核
- 預(yù)測分子量21.6kDa
- 實際分子量20kDa(差異分析請參閱說明書)
- 片段與標(biāo)簽Met272~Ser427 with N-terminal His Tag
- 緩沖液成份20mM Tris, 150mM NaCl緩沖液（pH8.0, 含有1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose和Proclin300）
- 性狀凍干粉
- 純度> 90%
- 等電點6.5
- 應(yīng)用Positive Control; Immunogen; SDS-PAGE; WB.
如果需要有生物活性的蛋白，請參見活性蛋白。 - 下載英文說明書 中文說明書
- 規(guī)格10μg50μg200μg1mg5mg
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產(chǎn)品包裝(模擬)
產(chǎn)品包裝(模擬)
Figure. SDS-PAGE
通過ISO 9001、ISO 13485質(zhì)量體系認(rèn)證
序列
用法
Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.
儲存
避免反復(fù)凍融。2-8°C不超過一個月，-80°C不超過12個月。
穩(wěn)定性
熱穩(wěn)定性以損失率顯示。損失率是由加速降解試驗決定，具體方法如下：在37°C孵育48小時，沒有顯著的降解或者沉淀產(chǎn)生。保質(zhì)期內(nèi)，在適當(dāng)?shù)臈l件下存儲，損失率低于5%。
增值服務(wù)
相關(guān)產(chǎn)品
| 編號 | 適用物種：Homo sapiens (Human，人) | 應(yīng)用(僅供研究使用，不用于臨床診斷！) |
| APA475Hu01 | 維生素D受體(VDR)活性蛋白 | Cell?culture;?Activity?Assays. |
| RPA475Hu01 | 維生素D受體(VDR)重組蛋白 | Positive Control; Immunogen; SDS-PAGE; WB. |
| PAA475Hu01 | 維生素D受體(VDR)多克隆抗體 | WB |
| MAA475Hu22 | 維生素D受體(VDR)單克隆抗體 | WB; IHC; ICC; IP. |
| SEA475Hu | 維生素D受體(VDR)檢測試劑盒(酶聯(lián)免疫吸附試驗法) | Enzyme-linked immunosorbent assay for Antigen Detection. |
| LMA475Hu | 維生素D受體(VDR)等多因子檢測試劑盒(流式熒光發(fā)光法) | FLIA Kit for Antigen Detection. |
參考文獻
| 雜志 | 參考文獻 |
| 6 | The vitamin D receptor: A therapeutic target for the treatment of breast cancer?[Cgi: Content] |
| endocrine-related cancer | Vitamin D receptor as a target for breast cancer therapy.[pubmed:28213567] |
| Journal of Advanced?Research | Effect?of?exercise?on?serum?vitamin D?and?tissue?vitamin Dreceptors?in?experimentally?induced?type 2 Diabetes Mellitus.[pubmed:27504197] |
| European Journal of Applied Physiology | Vitamin D supplementation attenuates oxidative stress in paraspinal skeletal muscles in patients with low back pain[Pubmed:29143122] |
| BBA- Molecular Basis of Disease | Enhanced remedial effects for vitamin D3 and calcium co-supplementation against pre-existing lead nephrotoxicity in mice: The roles of renal calcium homeostatic?…[Pubmed: 30553018] |
| OPEN ACCESS MACEDONIAN JOURNAL OF MEDICAL SCIENCES | Seluang Fish (Rasbora Spp.) Oil Decreases Inflammatory Cytokines Via Increasing Vitamin D Level in Systemic Lupus Erythematosus[] |
| Journal of Steroid Biochemistry and Molecular Biology | Status of vitamin D and the associated host factors in pulmonary tuberculosis patients and their household contacts: a cross sectional study[Pubmed: 31255688] |
| Scientific Reports | Association of Fok1 VDR polymorphism with Vitamin D and its associated molecules in pulmonary tuberculosis patients and their household contacts[Pubmed: 31649297] |
| Research square | Vitamin D Status in Dupuytren's Disease: Association with Clinical Status and Vitamin D Receptor Expression[] |
| Betok Fish (Anabas testudineus) Oil Decreases Inflammatory Cytokine through Increasing Vitamin D Level in Rats-induced Systemic Lupus Erythematosus[] | |
| iium medical journal malaysia | Positive Correlation between Monocyte-to-Lymphocyte Ratio and C-Reactive Protein in Vitamin D Deficient Preterm Infants with Respiratory Distress Syndrome[] |
| Research Square | Identification of SNP of VDR and VDBP gene and its Dysregulated pathway through VDR-VDBP interaction network analysis in Vitamin D deficient Infertile?…[] |